3D Cell Culture Platform

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A New Standard for 3D Cell Culture

Our platform, which includes VersaGel®, Symphony® and a simple cell encapsulation protocol, supports benchtop researchers and screening groups creating in vitro cultures and ex vivo organoids.

Check out our new paper on patient/PDX tumor testing in VersaGel, published in Molecular Cancer Therapeutics!

Fabulous instrument and tools produced by Cypre. The versatility and ease of use of Versagel is a leap forward compared to traditional basement membrane matrices. The imaging capabilities enable phenotypic screen with an unprecedented resolution and clarity.
— Felipe de Sousa e Melo, Genentech, SelectScience Review

Versagel


T cell infiltration into VersaGel and tumor killing
We were able to adapt the Symphony/VersaGel platform to generate optimized plating conditions that would have been impossible with traditional matrices.
— Donnie MacKenzie, BioMarin Pharmaceutical, SelectScience Review

VersaGel® is a light-crosslinkable ECM hydrogel for 3D in vitro & ex vivo assays

The tunable ECM hydrogel recapitulates human physiology and supports many cell types.

  • Cell adhesion through integrin binding sites

  • MMP-degradable for 3D cell growth and invasion

  • Optical clarity allows for superior high content analysis and better results

  • Microporous membrane for efficient nutrient, drug and gas exchange

  • Easy 30-minute digestion protocol enables downstream analysis flexibility

  • Batch consistency ensures reproducible results

  • Simple handling characteristics make 3D culture accessible to anyone

Symphony


Symphony® is our easy to use instrument that solidifies VersaGel in standard microwell plates in 60 seconds

“Small footprint, big impact”.

Slightly bigger than a box of pipette tips, Symphony fits right in your biosafety hood. And with 1-button, you can make a plate your first day.

60 seconds per plate, then add media and incubate.

Unlock the power of VersaGel with the Symphony.

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“I found the Symphony with the accompanying VersaGel much easier to use than any of my previous 3D gel formats. I would certainly recommend it.
— Jayne Helsey, Molecular Devices, SelectScience Review